A Review on Futuristic Scope of Agents Related to Amphibian’s Skin and Plants-based Sources in Type 2 Antidiabetic Therapies

Journal of Pharmacy Practice and Community Medicine,2022,8,3,36-41.
Published:September 2022
Type:Review Article
Author(s) affiliations:

Shipra Tripathi1, Vaibhav Dubey2, Alok Semwal3,*, Ratan B Chaturvedi4, Vishal Musale5, Kamal Narain6

1Ambkeshwar Institute of Pharmaceutical Sciences, BKT, Lucknow, Uttar Pradesh, INDIA.

2Volhart Health Care Pvt. Ltd., Department of Research and Development, Lucknow, Uttar Pradesh, INDIA.

3College of Pharmacy, Shivalik Campus, Dehradun, Uttarakhand, INDIA.

4Mountain Side Hospital, Pompton Avenue, Cedar Grove, New Jersey, USA.

5School of Medicine, University of Dundee, Nethergate, Dundee, Scotland, UK.

6AIMST University, Bedong, Kedah, MALAYSIA.


Based on the current scenario type-2 diabetes has been labelled as one of the major health issues, approaching exponentially towards mind boggling stage of epidemic globally. Considering to its lifelong latency from early to old ages, less awareness to its particular genotype and phenotype and hefty cost involved in its management and treatment; there is substantial need for more advance, personalised and economical therapeutic approaches for its effective therapy and treatment. The current review here discusses peculiar agents from amphibian’s skin and rarely explored distinctive plant sources with potential to be a viable therapeutic option for type-2 diabetes, therefore, could be devised into effective future treatment strategy to it and also to its related microvascular and macrovascular complications. Based on the literature search the therapeutic scope of agents from amphibian’s skin and selected plants sources are delineated, sighting their activities and prospects as to be future revolutionary remedy to type-2 diabetes and associated hitches such as their insulin releasing ability in pancreatic beta cell lines and primary islets cells, effects on glucose level and on other metabolic parameters such as obesity, lipid profile and pancreatic beta cell function etc.