Case Series
Journal of Pharmacy Practice and Community Medicine
Vol. 4
Issue 2
2018
pp. 128-130
Open Access

Isoniazid Induced Liver Injury; A Case Series and Review

Ramatati Anusha1,Sharad Chand1,Varun Lal1,Devarapu Mary Sushmitha1,Dhypa Sahithi Reddy1,Siddha Tejaswini1,Savanthi Chitrahasini1
1Department of Pharmacy Practice, TVM College of Pharmacy, Ballari-583103, Karnataka, INDIA.
Correspondence:

*Ramatati Anusha

Department of Pharmacy Practice, TVM College of Pharmacy, Ballari-583103, Karnataka, INDIA.

anugracy.94@gmail.com

Copyright:

2018 Author(s)

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Published:20/06/2018
Received: 16/03/2018
Accepted: 27/05/2018

Abstract

Isoniazid is one of the most common drugs inducing liver injury, identifying and quantification of risk related to the drug is the prime to prevent and treat its occurrence. This case series tried to demonstrate the risk of drug (Isoniazid) by using the various causality assessment scales (RUCAM/CIOMS and Narnajo Algorithm). The cases taken were all males and taking the medication which on course develops the hepatotoxicity. It might be used as the literature for further study in addition similar studies are need to be carried out to understand the risk factor of drug induced liver injury.

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Keywords

Isoniazid
Antitubercular therapy
Drug-induced liver injury
Hepatotoxicity

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