Case Report
Journal of Pharmacy Practice and Community Medicine
Vol. 12
Issue 3
2026
pp. 191-195
Open Access

A Case Reports On Bilateral Diffuse Cystic Lung Disease (Pulmonary Langerhans’ Cell Histiocytosis)

Faizan Ali Shaik1,Snehitha Kasu1,Kedareswari Jonnadula1,Hemalatha Ganjala1,Hima Sathwika Manchikanti1,Sandhya Kota1,Ramya Valaparla1
1Department of Pharmacy Practice, Pharmacology, Nirmala College of Pharmacy, Acharya Nagarjuna University, Atmakur, Mangalagiri, Guntur, Andhra Pradesh, INDIA.
Correspondence:

*Snehitha Kasu

Department of Pharmacy Practice, Pharmacology, Nirmala College of Pharmacy, Acharya Nagarjuna University, Atmakur, Mangalagiri, Guntur, Andhra Pradesh, INDIA.

snehithakasu@gmail.com

Copyright:

2026 Author(s)

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Published:22/05/2026
Received: Not set
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Abstract

Diffuse Cystic Lung Disease (DCLD) is an uncommon and complex condition marked by the presence of numerous air-filled cysts scattered throughout the lung tissue. This case report discusses about a 67-year-old man who came to the hospital with symptoms including nausea, vomiting, fever, persistent cough, and chest discomfort. His medical background was notable for rheumatoid arthritis, Hypothyroidism, Cholelithiasis, and Grade I Fatty Liver Infiltration, along with a history of undergoing coronary artery angiography. Imaging studies revealed a collapse and consolidation in the lower lobe of the left lung, alongside multiple cysts in both lungs and areas of ground-glass opacity. Blood tests indicated signs of inflammation and abnormalities in hematological and liver function parameters. Based on the clinical and radiological findings, a final diagnosis of bilateral DCLD Pulmonary langerhans cell histiocytosis, was made. The patient was managed with bronchodilators, corticosteroids, NSAID’s, analgesics, and antiemetics. This case underscores the diagnostic complexity and therapeutic challenges of DCLD, emphasizing the urgent need for more research to enhance early detection and improve treatment outcomes.

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Keywords

Diffuse cystic lung disease
Lung cysts
Collapse consolidation
Diagnosis
Treatment
challenges

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